THE FEATURES OF 3,4-METHYLENEDIOXYPYROVALERONE STUDY AND THE DIFFERENTIATION OF ITS POSSIBLE MIXTURES WITH METHADONE AND COCAINE

Abstract

The authors outline features of 3,4-methylenedioxypyrovalerone study using qualitative chemical reactions, thin-layer chromatography, gas-liquid chromatography with mass-selective and flame-ionization detection, liquid chromatography with mass spectrometric detection in this article. Its general characteristic, physical and chemical properties are specified; as well as the attention was focused on the differences in the 3,4-methylenedioxypyrovalerone, methadone and cocaine during the study by methods of qualitative chemical reactions and thin-layer chromatography. The results of experimental data on color change during qualitative chemical reactions of three substances with seven reagents are substantiated. The results of two reactions to the identification of methadone and three to the definition of cocaine were singled out. The article shows the characteristic feature of 3,4-methylenedioxypyrovalerone,  which appears on the plate for thin-layer chromatography in ultraviolet light (254 and 366 nm), and allows us to make assumptions about possible substances. Moreover, the results of the experimental data of chromatography in four systems for thin-layer chromatography are, which make it possible to obtain the maximum difference of the Rf values between methadone, cocaine and 3,4-methylenedioxypyrovalerone.
Key words: 3,4-methylenedioxypyrovalerone; methadone; cocaine; qualitative chemical reactions; thin-layer chromatography; gas-liquid chromatography; liquid  chromatography.